| Product Name | CD68 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [514H12] to CD68This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
| Immunogen | Fusion protein corresponding to external domain of human CD68 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 514H12 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FIHC-P |
| Immunohistology - Paraffin: 1/40 - 1/80 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LAMP4 CD68 molecule SCARD1 GP110 |
|---|---|
| Target | CD68 |
| Tissue Specificity | This antibody recognizes human CD68. |
| Application Notes | Immunohistology - Paraffin: 1/40 - 1/80 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.09%Sodium Azide |
