Mouse Monoclonal antibody [FN50] to CD69CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.Entrez Gene: 12p13-p12
Immunogen
anti-µ-stimulated human B lymphocytes
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
FN50
Host Species
Mouse
Tested Applications
FACSIHC-FFunctional Assay
FACS: Use at 5 µg/mL:
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CLEC2C
Target
CD69
Tissue Specificity
The antibody FN50 recognizes CD69, an lymphocyte early activation marker.
Application
Application
Surface staining of human peripheral blood using anti-CD69 antibody (clone FN50) after overnight activation of T cells by anti-CD3 (clone MEM-57).
Application Notes
FACS: Use at 5 µg/mL:
Additional Information
Form
Liquid
Storage Instructions
Store at 2-8°C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4