Application
IHC-P analysis of human tonsil tissue using CD8 antibody [4B11].| Product Name | CD8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [4B11] to CD8The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Immunogen | Synthetic peptide derived from CD8 alpha chain sequence. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 4B11 |
| Host Species | Mouse |
| Tested Applications | IHC-FIHC-PWB |
| Immunohistology - Frozen: 1/20 - 1/40: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | p32 CD8a molecule MAL Leu2 CD8A |
|---|---|
| Target | CD8 |
| Tissue Specificity | This antibody recognizes human CD8. |
Application
IHC-P analysis of human tonsil tissue using CD8 antibody [4B11].| Application Notes | Immunohistology - Frozen: 1/20 - 1/40: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.09%Sodium Azide |
