Mouse monoclonal antibody [RAVB3] to CD8The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Immunogen
The immunogen corresponding to human CD8 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
RAVB3
Host Species
Mouse
Tested Applications
ELISAFACS
ELISA: 1/10000.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
MAL CD8A LEU2 P32
Target
CD8
Application
Application
Flow cytometric analysis of peripheral blood T cells using anti-CD8 monoclonal antibody
Application
Flow cytometric analysis of blood T cells using CD8 mouse mAb (M2) and negative control (M1).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.
Storage Buffer
Purified antibody in PBS containing 0.03% sodium azide.