Rabbit Polyclonal antibody to CDC37 (cell division cycle 37)The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human CDC37. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, Chicken, BovineMouse (95%), Rat (90%), Pig (97%), Chicken (85%), Bovine (98%)
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
P50CDC37 cell division cycle 37
Target
CDC37
Molecular Weight(MW)
44 kDa (note)
Cellular Localization
Cytoplasm
Application
Application
CDC37 antibody detects CDC37 protein by western blot analysis. A. 30 μg Jurkat whole cell lysate/extract B. 30 μg Raji whole cell lysate/extract C. 30 μg NCI-H929 whole cell lysate/extract 10 % SDS-PAGE CDC37 antibody dilution: 1:5000
Positive Control
Jurkat , Raji , NCI-H929
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.