Application
Sample (50 ug of whole cell lysate) A: mouse heart 12% SDS PAGE diluted at 1:1000| Product Name | CDC42EP2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CDC42EP2 (CDC42 effector protein (Rho GTPase binding) 2)CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Rhesus Monkey, BovineHuman (100%), Rat (89%), Rhesus Monkey (99%), Bovine (88%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BORG1 antibody CEP2 antibody CDC42EP2 antibody CRIB-containing BOGR1 protein antibody cdc42 effector protein 2 antibody binder of Rho GTPases 1 antibody CDC42 effector protein (Rho GTPase binding) 2 antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa (note) (2) |
| Cellular Localization | Endomembrane system , Cytoplasm , cytoskeleton |
Application
Sample (50 ug of whole cell lysate) A: mouse heart 12% SDS PAGE diluted at 1:1000| Positive Control | mouse heart |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
