Rabbit Polyclonal antibody to CDCA7L (cell division cycle associated 7-like)Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Immunogen
Recombinant protein encompassing a sequence within the center region of human CDCA7L. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Rhesus Monkey, Chimpanzee, BovineMouse (87%), Rat (85%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (88%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)