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CDK6 antibody

Catalog Number:OM246527
OM246527
Discount Price
OM246527-100ul
1~2 Week
100ul
OM246527-50ul
50ul
OM246527-20ul
20ul
1~2 Week
Product Profile
Product Name CDK6 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to CDK6The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]
Immunogen Recombinant protein of human CDK6
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:100:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms cyclin-dependent kinase 6
PLSTIRE
Target CDK6
Application

Application

Western blot analysis of extracts of various cell lines, using CDK6 antibody.

Application

Immunohistochemistry of paraffin-embedded rat lung using CDK6 antibody at dilution of 1:100 (x400 lens).

Application

Immunohistochemistry of paraffin-embedded human stomach cancer using CDK6 antibody at dilution of 1:200 (400x lens).

Application

Immunohistochemistry of paraffin-embedded human colon cancer tissue using CDK6 antibody.
Application Notes WB: 1:500 - 1:2000. IHC: 1:50 - 1:100:
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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