Application
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE diluted at 1:10000Application
CDS1 antibody [C1C3] detects CDS1 protein at cytosol on mouse stomach by immunohistochemical analysis. Sample: Paraffin-embedded mouse stomach. CDS1 antibody [C1C3] dilution: 1:500.| Product Name | CDS1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CDS1 (CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1)Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CDS1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, PigRat (96%), Pig (96%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CDS antibody CDS1 antibody phosphatidate cytidylyltransferase 1 antibody CDP-DAG synthase 1 antibody CDS 1 antibody CDP-diglyceride synthetase 1 antibody CDP-diglyceride pyrophosphorylase 1 antibody CTP:phosphatidate cytidylyltransferase 1 antibody |
|---|---|
| Molecular Weight(MW) | 53 kDa (note) |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein , Endoplasmic reticulum membrane |
Application
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE diluted at 1:10000
Application
CDS1 antibody [C1C3] detects CDS1 protein at cytosol on mouse stomach by immunohistochemical analysis. Sample: Paraffin-embedded mouse stomach. CDS1 antibody [C1C3] dilution: 1:500.| Positive Control | A431 , H1299 , HeLa , Molt-4 , Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
