| Product Name | CENPJ antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CENPJ (centromere protein J)This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CENPJ. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Rat, ChimpanzeeHuman (100%), Mouse (92%), Rat (93%), Chimpanzee (99%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BM032 antibody CPAP antibody LAP antibody LIP1 antibody MCPH6 antibody MGC131581 antibody MGC131582 antibody MGC142222 antibody MGC142224 antibody SASS4 antibody SCKL4 antibody Sas-4 antibody CENPJ antibody centrosomal P4.1-associated protein |
|---|---|
| Target | CENPJ |
| Molecular Weight(MW) | 153 kDa (note) |
| Cellular Localization | Centrosome , Cytoplasm , cytoskeleton |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
