| Product Name | c-Fos antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [CF1] to c-FosThis antibody is reactive with c-fos protein in a large proportion of breast carcinomas. The c-fos protein, a 62 kD nuclear protein, becomes a transcriptionally active complex with properties of the transcription factor AP-1 when associated with c-jun protein. |
| Immunogen | The immunogen corresponding to a region within amino acids 120 and 155 of human c-Fos. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | CF1 |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIHC-FIHC-PIPWB |
| ImmunohistochemistryThis antibody can be used on frozen tissue sections only. For a three-step avidin-biotin complex system, a dilution of 1:20 to 1:40 may be used as a guideline. An overnight incubation with the primary antibody at 4°C produces the most consistent and reproducible results. The optimal conditions should be determined by the individual laboratory.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 2353 FOS 164810 c-fos cFos P01100 c Fos AP-1 AP 1 AP1 |
|---|---|
| Target | c-Fos |
| Tissue Specificity | Reacts with the 62kD human c-fos protein. |
| Cellular Localization | Nuclear |
| Positive Control | A large proportion of breast cancers are positive. |
|---|---|
| Application Notes | ImmunohistochemistryThis antibody can be used on frozen tissue sections only. For a three-step avidin-biotin complex system, a dilution of 1:20 to 1:40 may be used as a guideline. An overnight incubation with the primary antibody at 4°C produces the most consistent and reproducible results. The optimal conditions should be determined by the individual laboratory.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, containing 1% BSA and 0.09% sodium azide |
