Mouse monoclonal antibody [INN-hCG-22] to CG betaThis gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
INN-hCG-22
Host Species
Mouse
Tested Applications
ELISAIAIHC-PWB
ELISA: 1/100 - 1/500:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CGB8 CGB7 CGB CGB5 HCGB CGB3
Target
CG beta 2
Tissue Specificity
This antibody shows strong reaction in RIA with hCG and hCG beta. Some reactivity was found on hLH (12%) and hLH beta (34%). No reaction with hFSH, hTSH, hCG alpha and hLH alpha. Affinity constant = 1.6 x 109m (Ka) .
Application Notes
ELISA: 1/100 - 1/500:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.