| Product Name | cGMP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to cGMPCyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG). |
| Immunogen | Chemical / Small Molecule (cyclic GMP-2'-O-HS) conjugated to BSA. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | RIA |
| RIA: Use at a dilution of 1/10. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Other |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Guanosine 3 5 Cyclic Monophosphate |
|---|---|
| Target | cGMP |
| Tissue Specificity | The product is specific for cGMP and does not cross-react with 5'-AMP, 5'-ADP, 5'-ATP, cAMP, Guanosine, 5'-GMP, 5'-GDP and 5'-GTP. |
| Application Notes | RIA: Use at a dilution of 1/10. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Reconstitute with 1 ml 0.1% BSA in distilled water |
