| Product Name | CHMP2A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CHMP2A (chromatin modifying protein 2A)CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CHMP2A. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Predicted Reactivity | Human, Mouse, Rat, Xenopus laevis, Rhesus Monkey, BovineHuman (100%), Mouse (99%), Rat (99%), Xenopus laevis (82%), Rhesus Monkey (100%), Bovine (97%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BC-2 antibody, BC2 antibody, CHMP2 antibody, VPS2 antibody, VPS2A antibody, CHMP2A antibody, vacuolar protein sorting-associated protein 2-1 antibody, chromatin modifying protein 2A antibody, putative breast adenocarcinoma marker (32kD) antibody, putative |
|---|---|
| Molecular Weight(MW) | 25 kDa (note) |
| Cellular Localization | Late endosome membrane |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
