Application
WB analysis of human thymus tissue using Choroideremia antibody at 0.2-1μg/ml.| Product Name | Choroideremia antibody, N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ChoroideremiaThis gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009] |
| Immunogen | A synthetic peptide corresponding to a N-terminal region of Human Choroideremia |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Horse: 80%; Human: 100% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | REP1 , DXS540 , HSD32 , CHM , GGTA , TCD |
|---|---|
| Target | Choroideremia |
| Molecular Weight(MW) | 73 KDa (note) |
Application
WB analysis of human thymus tissue using Choroideremia antibody at 0.2-1μg/ml.| Positive Control | human thymus |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
