Application
Formalin fixed paraffin embedded human pancreas stained with Chromogranin antibody (cat. # ).Application
Human Colon stained with anti-Chromogranin A antibodyApplication
Human Stomach Adenocarcinoma stained with anti-Chromogranin A antibodyApplication
Human Stomach stained with anti-Chromogranin A antibodyApplication
Human Prostate stained with anti-Chromogranin A antibodyApplication
Human Pituitary stained with anti-Chromogranin A antibodyApplication
Human Pancreas stained with anti-Chromogranin A antibodyApplication
Human Pancreatic Adenocarcinoma stained with anti-Chromogranin A antibody| Product Name | Chromogranin A antibody [SP12] (ready-to-use) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Monoclonal Rabbit Antibody to Human Chromogranin AThe protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq] |
| Immunogen | Recombinant protein encoding human Chromogranin A. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | SP12 |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-P |
| We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | P10645, CGA, 1113, CHGA, 118910, Chromogranin A |
|---|---|
| Target | Chromogranin A |
| Tissue Specificity | This antibody recognizes Chromogranin A. Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.This antibody crossreacts with Human. |
| Cellular Localization | Cytoplasmic |
Application
Formalin fixed paraffin embedded human pancreas stained with Chromogranin antibody (cat. # ).
Application
Human Colon stained with anti-Chromogranin A antibody
Application
Human Stomach Adenocarcinoma stained with anti-Chromogranin A antibody
Application
Human Stomach stained with anti-Chromogranin A antibody
Application
Human Prostate stained with anti-Chromogranin A antibody
Application
Human Pituitary stained with anti-Chromogranin A antibody
Application
Human Pancreas stained with anti-Chromogranin A antibody
Application
Human Pancreatic Adenocarcinoma stained with anti-Chromogranin A antibody| Positive Control | Pancreas |
|---|---|
| Application Notes | We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
