Application
Western blot analysis of cIAP-1 in Mouse small intestine tissue lysate.| Product Name | cIAP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to cIAP1Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and –7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Mouse small intestine and rat kidney tissue lysate can be used as positive controls | |
| Species Reactivity | MouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | API1, BIRC2, IAP2, MIHB, RNF48, HIAP2, HIAP-2, C-IAP1, CIAP1, HIAP 2, C IAP1 |
|---|---|
| Target | cIAP1 |
| Tissue Specificity | This antibody is specific for cIAP-1. |
Application
Western blot analysis of cIAP-1 in Mouse small intestine tissue lysate.| Application Notes | Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Mouse small intestine and rat kidney tissue lysate can be used as positive controls |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
