Application
Western blot analysis of cIAP-2 in Jurkat cell Lysate.| Product Name | cIAP2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to cIAP2Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and ~7. For example, XIAP, cIAP 1 and cIAP 2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP 1 and cIAP 2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms. |
| Immunogen | Available on request. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a concentration of 1 - 3 μg/ml. In Western blot, this antibody detects a band of approximately 68 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse(88%),Rat(85%) |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MALT2, RNF49, 330, HAIP1, MIHC, Q13489, API2, BIRC3, AIP1, HIAP1, 601721, CIAP2, c-IAP2, c IAP2 |
|---|---|
| Target | cIAP2 |
Application
Western blot analysis of cIAP-2 in Jurkat cell Lysate.| Application Notes | WB: Use at a concentration of 1 - 3 μg/ml. In Western blot, this antibody detects a band of approximately 68 kDa. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS with 1 mg/ml BSA, 1.5 mM sodium azide and 50% glycerol |
