Application
Immunohistochemical staining of CIDE-A in human brain tissue with CIDE-A antibody at 5μg/mlApplication
Western blot analysis of CIDE-A in human brain tissue lysate in the absence (A) or presence (B) of immunogenic peptide with CIDE-A antibody at 0.5ug/ml.| Product Name | CIDE A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to CIDE-AApoptosis is related to many diseases and is induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD (1-3). DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues. |
| Immunogen | Synthetic peptide - corresponding to amino acids 200-217 of Human CIDE-A |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB: Use at a dilution of 1:1,000-1:2,000. Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CIDE A, 604440, CIDEA, 1149, O60543, CIDE-A |
|---|---|
| Target | CIDE A |
| Tissue Specificity | This antibody has no cross-reactivity to CIDE B |
Application
Immunohistochemical staining of CIDE-A in human brain tissue with CIDE-A antibody at 5μg/ml
Application
Western blot analysis of CIDE-A in human brain tissue lysate in the absence (A) or presence (B) of immunogenic peptide with CIDE-A antibody at 0.5ug/ml.| Positive Control | Human brain tissue lysate |
|---|---|
| Application Notes | For WB: Use at a dilution of 1:1,000-1:2,000. Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.02% sodium azide |
