| Product Name | CIDEC antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to human CIDECDNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blot - Use at 1:500-1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CIDE3, Cell Death Activator Cell Death Inducing DFFA Like Effector C CIDE3 CIDEC FLJ20871 FSP27, CIDE-3, Fsp27, CIDE 3 |
|---|---|
| Target | CIDEC |
| Tissue Specificity | Reacts with residues 10-25 [LLYPKSLSRHVSVRTS] of the 27 kDa human CIDEC protein. Cross reactivity to FSP27, which is the mouse homolog of CIDE-3: 93% sequence identity. |
| Application Notes | Western blot - Use at 1:500-1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
