| Product Name | c-Kit antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [14G5] to c-KitThis gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to a region within amino acid 26 and 520 of human SCF-R (extracellular domain) (Swiss-Prot entry P10721). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 14G5 |
| Host Species | Mouse |
| Tested Applications | NeutWB |
| WB(1:500-1000)|Neutralization of SCF-R bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | C-Kit PBT KIT CD117 SCFR v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
|---|---|
| Target | c-Kit |
| Tissue Specificity | This antibody was selected for its ability to detect human SCF-R. |
| Application Notes | WB(1:500-1000)|Neutralization of SCF-R bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
