Application
IHC-Fr analysis of mouse lung tissue using Claudin 10 antibody [4B8A12] (green), ZO-1 antibody (red) and DAPI (blue).| Product Name | Claudin 10 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [4B8A12] to Claudin 10This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010] |
| Immunogen | Mixture of two peptides from the middle and C-terminal regions of human claudin-10 protein (accession # P78369, NP_008915 for human isoform b, and NP_878268 for human isoform a), which is 88% homologous with rat isoforms a and b, and 86% omologous with mou |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4B8A12 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FIHC-PWB |
| ICC/IF:1:100~1:200 IHC-F:1:20~1:50 IHC-P:1:20~1:100 WB:1:250~1:1000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CPETRL3 claudin 10 OSP-L CLDN10 |
|---|---|
| Target | Claudin 10 |
Application
IHC-Fr analysis of mouse lung tissue using Claudin 10 antibody [4B8A12] (green), ZO-1 antibody (red) and DAPI (blue).| Application Notes | ICC/IF:1:100~1:200 IHC-F:1:20~1:50 IHC-P:1:20~1:100 WB:1:250~1:1000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C. |
| Storage Buffer | PBS, pH 7.4, containing 0.1% sodium azide. |
