Rabbit Polyclonal antibody to Claudin 4The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
Immunogen
CLAUDIN4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CLAUDIN4.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
IF: 20 ug/mL:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
At least four isoforms of CLAUDIN4 are known to exist; CLAUDIN4 antibody will detect all four isoforms
Application
Application
Immunofluorescence of CLAUDIN4 in human colon tissue with CLAUDIN4 antibody at 20 ug/mL.
Application
Western blot analysis of CLAUDIN4 in human colon tissue lysate with CLAUDIN4 antibody at 1 ug/ml
Application Notes
IF: 20 ug/mL:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.