Rabbit polyclonal to Claudin 4 predilutedClaudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.
Immunogen
Synthetic peptide (Human) (C terminal).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-P
IHC-P: Ready to use. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
O14493 WBSCR8 602909 CPER hCPER CLDN4 hCPE-R CPETR CPE-R CPETR1 1364 Claudin4 Claudin 4 CPE R hCPE R
Target
Claudin 4
Cellular Localization
Cell Membrane
Application
Application
Human tonsil stained with
Application
Human Ovarian Carcinoma stained with anti-Claudin-4 antibody
Positive Control
Tonsil, ovarian carcinoma cells
Application Notes
IHC-P: Ready to use. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution and store at 4°C. Do not freeze.
Storage Buffer
PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide