Rabbit Polyclonal antibody to Claudin 5 (claudin 5)This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human Claudin 5. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, BovineMouse (88%), Rat (88%), Pig (90%), Bovine (90%)
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
AWAL antibody BEC1 antibody CPETRL1 antibody TMVCF antibody CLDN5 antibody TMDVCF antibody claudin-5 antibody transmembrane protein deleted in VCFS antibody transmembrane protein deleted in velocardiofacial syndrome antibody claudin 5 antibody
Molecular Weight(MW)
23 kDa (note) (3)
Cellular Localization
Cell junction , tight junction , Cell membrane
Application
Application
WB ImageSample (30 ug of whole cell lysate) A: NT2D1 12% SDS PAGE diluted at 1:1000
Positive Control
NT2D1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.