Application
Western blot analysis of extracts from 3T3 cells (Lane 2), using Claudin 7 (Phospho-Tyr210) Antibody. The lane on the left is treated with antigen-specific peptide.| Product Name | Claudin 7 (phospho Tyr210) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Claudin 7 (phospho Tyr210)This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010] |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 210 (S-K-E-Y(p)-V) derived from Human Claudin 7. |
| Modification | p-Tyr210 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | claudin 7 CLDN-7 CLDN7 Hs.84359 CPETRL2 CEPTRL2 claudin-1 |
|---|---|
| Target | Claudin 7 (phospho Tyr210) |
| Tissue Specificity | The antibody detects endogenous levels of Claudin 7 only when phosphorylated at tyrosine 210. |
Application
Western blot analysis of extracts from 3T3 cells (Lane 2), using Claudin 7 (Phospho-Tyr210) Antibody. The lane on the left is treated with antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
