Application
IHC-P analysis of human kidney tissue using Claudin 8 antibody at 4.0-8.0μg/ml.Application
WB analysis of HepG2 cells using Claudin 8 antibody at 0.5-1.0μg/ml.Application
WB analysis of 293T cells using Claudin 8 antibody at 1.0μg/ml.Application
IHC-P analysis of human intestine tissue using Claudin 8 antibody at 4.0-8.0μg/ml.| Product Name | Claudin 8 antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Claudin 8This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.[provided by RefSeq, May 2010] |
| Immunogen | A synthetic peptide corresponding to a C-terminal region of Human Claudin 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Cow: 85%; Dog: 77%; Horse: 85%; Human: 100%; Pig: 77%; Rabbit: 85%; Rat: 77% |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | CLDN8 |
|---|---|
| Target | Claudin 8 |
| Molecular Weight(MW) | 25 KDa (note) |
Application
IHC-P analysis of human kidney tissue using Claudin 8 antibody at 4.0-8.0μg/ml.
Application
WB analysis of HepG2 cells using Claudin 8 antibody at 0.5-1.0μg/ml.
Application
WB analysis of 293T cells using Claudin 8 antibody at 1.0μg/ml.
Application
IHC-P analysis of human intestine tissue using Claudin 8 antibody at 4.0-8.0μg/ml.| Positive Control | 293T , HepG2 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
