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c-Myc antibody

Catalog Number:OM247586
OM247586
Discount Price
OM247586-100ul
1~2 Week
100ul
OM247586-50ul
50ul
1~2 Week
Product Profile
Product Name c-Myc antibody
Antibody Type Tags Antibodies
Product description Mouse monoclonal antibody [7E10] to c-MycThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to human MYC expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 7E10
Host Species Mouse
Tested Applications ELISAWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms BHLHE39
MYC
MRTL
Target c-Myc
Molecular Weight(MW) 49 kDa (note)
Application

Application

Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng)

Application

Western blot analysis using MYC mAb against human MYC (AA:214-387) recombinant protein. (Expected MW is 44.7 kDa)
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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