Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using CNOT2 (Phospho-Ser101) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | CNOT2 (phospho Ser101) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CNOT2 (phospho Ser101)This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010] |
| Immunogen | Peptide sequence around phosphorylation site of Serine101(S-L-S(p)-Q-G) derived from Human CNOT2. |
| Modification | p-Ser101 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC: 1:50 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | NOT2H CNOT2 HSPC131 NOT2 CDC36 CCR4-NOT transcription complex subunit 2 |
|---|---|
| Target | CNOT2 (phospho Ser101) |
| Tissue Specificity | The antibody detects endogenous levels of CNOT2 only when phosphorylated at serine 101. |
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using CNOT2 (Phospho-Ser101) antibody (left) or the same antibody preincubated with blocking peptide (right).| Application Notes | IHC: 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
