| Product Name | COCO antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [25D4] to COCOThis gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008] |
| Immunogen | Recombinant Human COCO |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 25D4 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA(1:1000-2000): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GREM3 CERL2 CKTSF1B3 DANTE DAND5 CRL2 CER2 DAN domain family member 5 BMP antagonist SP1 |
|---|---|
| Target | COCO |
| Tissue Specificity | This antibody recognizes human COCO by ELISA. |
| Application Notes | ELISA(1:1000-2000): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
