| Product Name | Collagen XVII antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [NC16a-3] to Collagen XVIIThis gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008] |
| Immunogen | Collagen XVII. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | NC16a-3 |
| Host Species | Mouse |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF: 1:10. IHC-P: 1:2 - 1:40. WB: 1:100 - 1:10000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BPAG2 BP180 COL17A1 LAD-1 collagen type XVII alpha 1 BPA-2 BA16H23.2 |
|---|---|
| Target | Collagen XVII |
| Application Notes | ICC/IF: 1:10. IHC-P: 1:2 - 1:40. WB: 1:100 - 1:10000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Lyophilized antibody can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20ºC) or for long-term storage (-80ºC). |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
