Rabbit Polyclonal antibody to COLQ (collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase)This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human COLQ. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (87%), Rat (83%), Bovine (87%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
EAD antibody FLJ55041 antibody COLQ antibody single strand of homotrimeric collagen-like tail subunit of asymmetric acetylcholinesterase antibody acetylcholinesterase collagenic tail peptide antibody AChE Q subunit antibody acetylcholinesterase-assoc
Molecular Weight(MW)
48 kDa (note) (4)
Cellular Localization
Cell junction , synapse
Application
Application
Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using COLQ antibody at 1:500 dilution.
Positive Control
HepG2
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.