Application
Sample (30 ug of whole cell lysate) A: Zebrafish eye 10% SDS PAGE diluted at 1:1000Application
Cops5 antibody detects Cops5 protein on zebrafish by whole mount immunohistochemical analysis. Sample: 2 days-post-fertilization zebrafish embryo. Cops5 antibody dilution: 1:100.| Product Name | Cops5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to cops5 (COP9 constitutive photomorphogenic homolog subunit 5)Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity. In the complex, it probably acts as the catalytic center that mediates the cleavage of nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC-W |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | signalosome subunit 5 antibody, COP9 signalosome complex subunit 5 antibody, MGC73130 antibody, zgc:73130 antibody, cops5 antibody, COP9 constitutive photomorphogenic homolog subunit 5 antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa (note) |
| Cellular Localization | Cytoplasm , Nucleus |
Application
Sample (30 ug of whole cell lysate) A: Zebrafish eye 10% SDS PAGE diluted at 1:1000
Application
Cops5 antibody detects Cops5 protein on zebrafish by whole mount immunohistochemical analysis. Sample: 2 days-post-fertilization zebrafish embryo. Cops5 antibody dilution: 1:100.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
