Rabbit polyclonal antibody to Coronin 2A (coronin, actin binding protein, 2A)This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human Coronin 2A. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
BovineBovine (82%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CLIPINB antibody, DKFZp686G19226 antibody, IR10 antibody, WDR2 antibody, CORO2A antibody, coronin 2A antibody, coronin-2A antibody, coronin-like protein B antibody, WD protein IR10 antibody, WD repeat-containing protein 2 antibody, WD-repeat protein 2 anti
Target
Coronin 2A
Molecular Weight(MW)
60 kDa (note) (3)
Application
Application
Sample (30 ug of whole cell lysate) A: JurKat 7.5% SDS PAGE diluted at 1:1000
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.