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Corticotropin Releasing Factor antibody

Catalog Number:OM247952
OM247952
Discount Price
OM247952-100ul
1~2 Week
100ul
OM247952-50ul
50ul
OM247952-20ul
20ul
1~2 Week
Product Profile
Product Name Corticotropin Releasing Factor antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Corticotropin Releasing FactorCorticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
Immunogen CRH antibody was raised against a 16 amino acid peptide near the amino terminus of human CRH.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IFIHC-PWB
WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms corticotropin releasing hormone , CRF , CRH , CRH1
Target Corticotropin Releasing Factor
Tissue Specificity CRH antibody is human specific.
Application

Application

Immunofluorescence of CRH in human brain tissue with CRH antibody at 20 ug/mL.

Application

Western blot analysis of CRH in human placenta tissue lysate with CRH antibody at (A) 1 and (B) 2 ug/ml.

Application

Immunohistochemistry of CRH in human brain tissue with CRH antibody at 5 ug/mL.
Application Notes WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml
Additional Information
Form Liquid
Storage Instructions Be stored at 4oC for three months and -20oC, stable for up to one year.
Storage Buffer PBS containing 0.02% sodium azide.
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