Rabbit Polyclonal antibody to COX7BCytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22. [provided by RefSeq, Jun 2011]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human COX7B1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Species Reactivity
HumanMouseMonkeyRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
APLCC , cytochrome c oxidase subunit 7B
Target
COX7B
Tissue Specificity
Recognizes endogenous levels of COX7B1 protein.
Application
Application
Western blot analysis of COX7B1 expression in HeLa (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.