Rabbit Polyclonal antibody to C-PeptideAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human insulin. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISA
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Reactivity
Human, ChimpanzeeHuman (100%), Chimpanzee (100%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)