Rabbit Polyclonal antibody to CPI17 alphaInhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Immunogen
Peptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17 alpha .
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ICC/IF
Suggested starting dilutions are as follows. ICC/IF: 1:100~1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CPI-17, CPI17, PPP1INL, PPP1R14A, protein kinase C-potentiated inhibitor protein of 17 kDa, protein phosphatase 1 regulatory subunit 14A, 17-KDa protein, 17 kDa PKC-potentiated inhibitory protein of PP1, 17-kDa PKC-potentiated inhibitory protein of PP1, PK
Target
CPI17 alpha
Molecular Weight(MW)
17 (note)
Application
Application
Immunofluorescence staining of methanol-fixed Hela cells using CPI17a(Ab-38) Antibody
Application Notes
Suggested starting dilutions are as follows. ICC/IF: 1:100~1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.