Rabbit Polyclonal antibody to CPSF1 (cleavage and polyadenylation specific factor 1, 160kDa)Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human CPSF1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
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Predicted Reactivity
Human, Mouse, Rat, Zebrafish, Rhesus Monkey, BovineHuman (100%), Mouse (97%), Rat (98%), Zebrafish (80%), Rhesus Monkey (100%), Bovine (97%)