Rabbit Polyclonal antibody to CPT1A (carnitine palmitoyltransferase 1A (liver))The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human CPT1A. The exact sequence is proprietary.
Modification
Acetylated
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
wb:1:500~1:2000 IHC-P:1:50~1:500 *Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity
HumanMouseRat
Predicted Reactivity
Rat, Dog, Pig, Sheep, BovineRat (82%), Dog (86%), Pig (89%), Sheep (85%), Bovine (86%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)