Rabbit Polyclonal antibody to CREB3L1 (cAMP responsive element binding protein 3-like 1)Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.
Immunogen
Recombinant protein encompassing a sequence within the center region of human CREB3L1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (94%), Rat (93%), Bovine (94%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
OASIS antibody CREB3L1 antibody BBF-2 homolog antibody cyclic AMP-responsive element-binding protein 3-like protein 1 antibody old astrocyte specifically-induced substance antibody old astrocyte specifically induced substance antibody cAMP-responsive
Molecular Weight(MW)
57 kDa (note) (2)
Cellular Localization
Endoplasmic reticulum membrane , Processed cyclic AMP-responsive element-binding protein 3-like protein 1: Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: A549 7.5% SDS PAGE diluted at 1:500
Positive Control
A549
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.