Application
Application| Product Name | CRF-RII antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to Human CRF-RII ( CRHR2 )CRHR2, a Corticotropin-Releasing Factor Receptor is a neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Mutations of the receptor reduce coping behaviors to stress and increase basal blood pressure. Three isoforms of CRHR2 are produced by alternative splicing. CRHR2 expression has been reported in various regions of the brain, as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal, and skeletal muscle. CRCH2alpha is the dominant isoform and is expressed widely. CRCH2beta is expressed in the hippocampus, septum, amygdala, heart, and skeletal muscle. CRHR2gamma is brain-specific. ESTs have been isolated from brain libraries. |
| Immunogen | Synthetic peptide - KLH conjugated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 602034 CRFR2 1395 Q13324 CRHR2 |
|---|---|
| Target | CRHR2 |
Application
Application| Application Notes | Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate buffered saline, pH 7.4 containing 0.01% sodium azide |
