Application
Western blot analysis of CRMP2 (pS522) expression in HeLa (A); NIH3T3 (B) whole cell lysates.| Product Name | CRMP2 (phospho Ser522) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CRMP2 (phospho Ser522)This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CRMP2 (pS522). The exact sequence is proprietary. |
| Modification | p-Ser522 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | N2A3 , dihydropyrimidinase-like 2 , ULIP-2 , CRMP-2 , DHPRP2 , ULIP2 , DRP-2 , CRMP2 , DRP2 , DPYSL2 |
|---|---|
| Target | CRMP2 (phospho Ser522) |
| Tissue Specificity | Recognizes endogenous levels of CRMP2 (pS522) protein. |
Application
Western blot analysis of CRMP2 (pS522) expression in HeLa (A); NIH3T3 (B) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
