| Product Name | CRSP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CRSP1The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| Western blotting (1:500 – 1:2500 µg/ml), Immunoprecipitation. However, the optimal concentrations should be determined individually. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PPAR Binding Protein, 205 kD, RB18A, Cofactor Required for Sp1 Transcriptional Activation 1, Cofactor Required for Sp1 Transcriptional Activation1, PPARBP, Vitamin D Receptor Interacting Protein Complex Component, Thyroid Hormone Receptor-Associated Protei |
|---|---|
| Target | CRSP1 |
| Tissue Specificity | This antibody is specific for CRSP1. |
| Cellular Localization | A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3. |
| Application Notes | Western blotting (1:500 – 1:2500 µg/ml), Immunoprecipitation. However, the optimal concentrations should be determined individually. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 1% BSA and 0.02% thimerosal |
