| Product Name | CSE1L antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CSE1Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq] |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| Western blotting (1:1000 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. HeLa cell lysate can be used as a positive control. The antibody recognizes the CSE1 of human and mouse origins. Reactivity to other species has not been tested. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | XPO-2, Chromosome Segregation 1like, XPO2, CSE1, Chromosome Segregation1like, CSE1L, CAS, Chromosome Segregation 1-like, CSE-1, Cellular Apoptosis Susceptibility Protein, XPO 2, CSE 1, Chromosome Segregation 1 like |
|---|---|
| Target | CSE1 |
| Tissue Specificity | This antibody is specific for CSE1. |
| Cellular Localization | Shuttles between the nucleus and the cytoplasm. |
| Application Notes | Western blotting (1:1000 – 1:2500) and Immunoprecipitation. However, the optimal concentrations should be determined individually. HeLa cell lysate can be used as a positive control. The antibody recognizes the CSE1 of human and mouse origins. Reactivity to other species has not been tested. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 1% BSA and 0.02% thimerosal |
