Rabbit Polyclonal antibody to Ctip1This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human BCL11A
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BCL11A XL BCL11A BCL11a M BCL11A S B-cell CLL/lymphoma 11A HBFQTL5 ZNF856 CTIP1 EVI9 BCL11A L
Target
Ctip1
Application
Application
Western blot analysis of extracts of various cell lines, using BCL11A antibody.
Application
Immunohistochemistry of paraffin-embedded human liver cancer using BCL11A antibody at dilution of 1:200 (400x lens).