Rabbit polyclonal antibody to Cullin-4b (cullin 4b)This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human Cullin 4b. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Zebrafish, Xenopus laevis, CatMouse (98%), Rat (99%), Zebrafish (93%), Xenopus laevis (90%), Cat (99%)