Rabbit polyclonal to CX3CL1CX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.
Immunogen
Recombinant protein - rat CX3CL1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-FIHC-PIPWB
For IHC-Fr: Use at a dilution of 1:100-1:500. For IHC-P: Use at a dilution of 1:100-1:500. For WB: Use at a dilution of 1:1,000-1:2,000. For IP: Use at a dilution of 1:300-1:800. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
Rat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
Cx3c antibody Scyd1 antibody
Target
CX3CL1
Application
Application
Rat fractalkaline detected by Western blot in transfected (Lane 1) and untransfected (Lane 2) COS-7 cells
Positive Control
CX3CL1 transfected COS-7 cells
Application Notes
For IHC-Fr: Use at a dilution of 1:100-1:500. For IHC-P: Use at a dilution of 1:100-1:500. For WB: Use at a dilution of 1:1,000-1:2,000. For IP: Use at a dilution of 1:300-1:800. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.