| Product Name | CX3CR1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to CX3CR1CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2). |
| Immunogen | Synthetic peptide, corresponding to amino acids 175-189 of Human CX3CR 1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blot 1:500 - 50 kD band. Not yet tested in other applications.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Gene Synonyms | CMKDR1 1524 GPR13 P49238 V28 601470 GPRV28 CMKBRL1 CX3CR1 CCRL1 Fractalkine |
|---|---|
| Target | CX3CR1 |
| Tissue Specificity | This antibody recognizes human, mouse and rat CX3CR1 (50 kD). |
| Positive Control | THP-1 cell lysate |
|---|---|
| Application Notes | Western blot 1:500 - 50 kD band. Not yet tested in other applications.: |
| Form | Liquid |
|---|---|
| Storage Instructions | This antibody is stable for at least one (1) year at -20 °C. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, pH 7.4 |
