Rabbit polyclonal antibody to IP-10IP-10 (interferon-gamma induced protein 10 kDa; in mouse also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blot analysis (0.5-2 µg/ml). However, the optimal conditions should be determined individually.:
Species Reactivity
Rat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CXC motif chemokine10 IP 10 CXC motif chemokine 10 Smallinducible cytokine B10 10 kDa interferongammainduced protein GammaIP10 IP10 IP10 C-X-C mo Cxcl10 Small-inducible cytokine B10 10 kDa interferon-gamma-induced protein Gamma-IP10 IP
Target
IP-10
Tissue Specificity
This antibody is specific for IP-10.
Application
Application
Western blot analysis of IP-10 in EAE rat brain.
Application Notes
Western blot analysis (0.5-2 µg/ml). However, the optimal conditions should be determined individually.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.